abstract：GOAL:To prospectively assess the utility of multidetector row computed tomography angiography (MDCTA) in the diagnosis of active gastrointestinal bleeding (GIB). BACKGROUND:MDCTA is a relatively recent advance in CT scanning technology enabling excellent vascular visualization and detection of various vascular abnorma...

journal_title：Journal of clinical gastroenterology

authors： Sun H,Jin Z,Li X,Qian J,Yu J,Zhu F,Zhu H

更新日期：2012-01-01 00:00:00

abstract：:The human large intestine harbors a complex microbiota containing many hundreds of different bacterial species. Although structure/function relationships between different components of the microbiota are unclear, this complex multicellular entity plays an important role in maintaining homeostasis in the body. Many of...

journal_title：Journal of clinical gastroenterology

authors： Macfarlane GT,Macfarlane S

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Twenty-four-hour multichannel intraluminal impedance and pH (MII-pH) esophageal monitoring allows detection of both acid and nonacid gastroesophageal reflux episodes. The MII-pH catheter contains 6 impedance segments placed 3, 5, 7, 9, 15, and 17 cm above the lower esophageal sphincter (LES), plus a pH elect...

journal_title：Journal of clinical gastroenterology

authors： Hila A,Chowdhury N,Hajar N,Castell DO

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Nocturnal gastroesophageal reflux disease (GERD) has been associated with severe complications including erosive esophagitis, peptic stricture, and even esophageal adenocarcinoma and is known to cause a decreased health-related quality of life. However, there is limited information on independent predictors ...

journal_title：Journal of clinical gastroenterology

authors： Gaddam S,Maddur H,Wani S,Gupta N,Singh M,Singh V,Moloney B,Puli SR,Rastogi A,Bansal A,Sharma P

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND AIM:The role of alcohol consumption in insulin resistance remains unclear. The aim of this study was to examine the association between alcohol consumption and insulin resistance in a large asymptomatic population. METHODS:A total of 2463 asymptomatic Japanese men aged 28 years or above undergoing a com...

journal_title：Journal of clinical gastroenterology

authors： Gunji T,Matsuhashi N,Sato H,Iijima K,Fujibayashi K,Okumura M,Sasabe N,Urabe A

更新日期：2011-10-01 00:00:00

abstract：:Eosinophilic esophagitis is a recently described disease characterized by the presence of upper gastrointestinal tract symptoms in association with a dense esophageal eosinophilic infiltrate. The awareness and interest of physicians and researchers in this disease has been increasing as reflected by the number of publ...

journal_title：Journal of clinical gastroenterology

authors： Almansa C,Devault KR,Achem SR

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Although sessile serrated adenomas (SSAs) may represent a separate and important pathway for colorectal cancer (CRC), little is known about the risk factors for these lesions. Molecular abnormalities such as BRAF have been observed in SSA and smokers. Our hypothesis is that smoking may be associated with the...

journal_title：Journal of clinical gastroenterology

authors： Anderson JC,Rangasamy P,Rustagi T,Myers M,Sanders M,Vaziri H,Wu G,Birk JW,Protiva P

更新日期：2011-09-01 00:00:00

abstract：GOALS AND BACKGROUND:Nearly 40% of cytochrome P450 3A (CYP3A) activity is located in the small intestine. An earlier study has shown that cirrhotics with transjugular intrahepatic portosystemic shunts (TIPS) have diminished intestinal CYP3A activity. We hypothesized that oral CYP3A substrates known to prolong QT interv...

journal_title：Journal of clinical gastroenterology

authors： Vuppalanchi R,Juluri R,Ghabril M,Kim S,Thong N,Gorski JC,Chalasani N,Hall SD

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:This study was designed to determine whether a transjugular intrahepatic portosystemic shunt (TIPS) combined with embolotherapy was superior to TIPS alone. METHODS:Seventy-nine patients were included in the study (43 in the TIPS and embolotherapy group and 36 in the TIPS alone group). Embolotherapy was perfo...

journal_title：Journal of clinical gastroenterology

authors： Xiao T,Chen L,Chen W,Xu B,Long Q,Li R,Li L,Peng Z,Fang D,Wang R

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Although the efficacy of tacrolimus for inducing remission of refractory ulcerative colitis (UC) is established, its efficacy for maintaining remission of UC has not been evaluated. AIM:The aim of this study was to evaluate the efficacy of tacrolimus compared with thiopurines for maintaining remission in pa...

journal_title：Journal of clinical gastroenterology

authors： Yamamoto S,Nakase H,Matsuura M,Masuda S,Inui K,Chiba T

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Spiral enteroscopy (SE) has emerged as a new alternative for deep intubation of the small intestine. SE is most often used to evaluate abnormal findings on capsule endoscopy (CE). OBJECTIVE:Investigate the ability of SE to reproduce abnormal findings detected on preceding CE. DESIGN:Prospective study. SET...

journal_title：Journal of clinical gastroenterology

authors： Buscaglia JM,Richards R,Wilkinson MN,Judah JR,Lam Y,Nagula S,Draganov PV

更新日期：2011-04-01 00:00:00

abstract：:Despite the fact that sequential therapy has been evaluated in more than 2500 patients and has been shown to on average provide Helicobacter pylori eradication in 90% to 94%, some authorities still question whether it should be a first-line anti-H. pylori regimen. Here, we discuss H. pylori eradication using experienc...

journal_title：Journal of clinical gastroenterology

authors： Graham DY,Rimbara E

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is no consensus concerning small bowel preparation before capsule endoscopy (CE). This study evaluated the effects of 4 regimens on small bowel cleansing and diagnostic yield. METHODS:Patients were randomly divided into 4 groups. Group A consumed a clear liquid diet after lunch on the da...

journal_title：Journal of clinical gastroenterology

authors： Chen HB,Huang Y,Chen SY,Song HW,Li XL,Dai DL,Xie JT,He S,Zhao YY,Huang C,Zhang SJ,Yang LN

更新日期：2011-04-01 00:00:00

abstract：:We recently treated a patient with adult-onset Still's disease who developed macrophage activation syndrome (MAS) secondary to disseminated histoplasmosis while being treated with adalimumab. The gastroenterology service was consulted early, before diagnosis, as the patient presented with elevated liver enzymes and di...

journal_title：Journal of clinical gastroenterology

authors： Jayakar BA,Hashkes PJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Current methods to diagnose malignant biliary strictures are of low sensitivity. Confocal endomicroscopy is a new approach that may improve the diagnosis of indeterminate biliary strictures. The purpose of this study was to evaluate indeterminate biliary strictures using probe-based confocal laser e...

journal_title：Journal of clinical gastroenterology

authors： Loeser CS,Robert ME,Mennone A,Nathanson MH,Jamidar P

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Portal or bridging fibrosis is an indication for antiviral treatment in patients with chronic hepatitis B (CHB). An early marker predictive of liver fibrosis in hepatitis B e antigen (HBeAg)-negative CHB patients can alert clinicians to plan for treatment before disease progression. GOALS:To predict early a...

journal_title：Journal of clinical gastroenterology

authors： Lee IC,Chan CC,Huang YH,Huo TI,Chu CJ,Lai CR,Lee PC,Su CW,Hung HH,Wu JC,Lin HC,Lee SD

更新日期：2011-03-01 00:00:00

abstract：GOALS:To evaluate clinical, biochemical, and radiologic parameters at admission, which predict the development of acute pseudocyst (AP) after acute pancreatitis. BACKGROUND:There is limited data on factors that predict the development of AP. STUDY:Seventy-five consecutive patients with AP were prospectively enrolled ...

journal_title：Journal of clinical gastroenterology

authors： Poornachandra KS,Bhasin DK,Nagi B,Sinha SK,Rana SS,Shafiq N,Greer K,Gupta R,Kang M,Malhotra S,Singh K

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The metabolic fates of copper and iron are closely linked through ceruloplasmin and hephaestin. Ceruloplasmin is the principal copper carrying protein and decreases in acquired copper deficiency. Congenital absence of ceruloplasmin (aceruloplasminemia) results in tissue iron overload. Animal studies suggest ...

journal_title：Journal of clinical gastroenterology

authors： Thackeray EW,Sanderson SO,Fox JC,Kumar N

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Women with irritable bowel syndrome (IBS) frequently report chronic pelvic pain, however, it is still unanswered whether these are truly separate entities. IBS negatively impacts on quality of life, but the impact of IBS on sexual function is not clear. GOALS:We aimed to (1) describe the impact of IBS on se...

journal_title：Journal of clinical gastroenterology

authors： Choung RS,Herrick LM,Locke GR 3rd,Zinsmeister AR,Talley NJ

更新日期：2010-11-01 00:00:00

abstract：:Carcinoid metastases in the liver are typically solid, hypervascular lesions. We report 3 cases of cystic carcinoid tumors in the liver with radiographic findings. Two were metastatic from primary carcinoid tumors of the small intestine and one was not associated with any extra hepatic lesion at presentation or during...

journal_title：Journal of clinical gastroenterology

authors： Salamone L,McCarthy S,Salem RR

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND/AIM:We investigated changes in hepatitis B surface antigen (HBsAg) level and its correlation with clinical outcomes in treatment-naive chronic hepatitis B (CHB) patients undergoing entecavir therapy. PATIENTS AND METHODS:Among 51 hepatitis B e antigen (HBeAg)-positive treatment-naive CHB patients receiving ...

journal_title：Journal of clinical gastroenterology

authors： Jung YK,Kim JH,Lee YS,Lee HJ,Yoon E,Jung ES,Hong SK,Joo MK,Yeon JE,Park JJ,Kim JS,Bak YT,Byun KS

更新日期：2010-10-01 00:00:00

abstract：:Ammonia is a neurotoxin that is normally cleared by the intact liver and if not, hyperammonemia results in hepatic encephalopathy. Hyperammonemia may be owing to primary or secondary causes. Early diagnosis is important to prevent permanent brain damage. Advanced malignancy involving the liver is associated with hyper...

journal_title：Journal of clinical gastroenterology

authors： Broadbridge V,Townsend A,Pittman K,Kimber R,Patterson W,Sukumaran S,Price TJ

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The current prevalence of primary antibiotic resistance of H. pylori is not known in Korea. This study was done to evaluate the prevalence of primary antibiotic resistance of H. pylori, and to evaluate the effect of point mutations of 23S rRNA on the rate of eradication of H. pylori. METHODS:H. pylori were ...

journal_title：Journal of clinical gastroenterology

authors： Hwang TJ,Kim N,Kim HB,Lee BH,Nam RH,Park JH,Lee MK,Park YS,Lee DH,Jung HC,Song IS

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Beneficial findings concerning probiotics are increasing day by day. However, one of the most important parameter which affects the probiotic activity of a microorganism is its survival during the gastroduodenal transit. Some microencapsulation techniques could be applied to bacterial cells to improve this p...

journal_title：Journal of clinical gastroenterology

authors： Del Piano M,Carmagnola S,Andorno S,Pagliarulo M,Tari R,Mogna L,Strozzi GP,Sforza F,Capurso L

更新日期：2010-09-01 00:00:00

abstract：GOALS:To determine whether the consumption of artichokes enriched with a probiotic Lactobacillus paracasei strain affects fecal microbiota composition, fecal enzyme activity, and short-chain fatty acids production and symptom profile in patients suffering from constipation. BACKGROUND:Constipation is a common gastroin...

journal_title：Journal of clinical gastroenterology

authors： Valerio F,Russo F,de Candia S,Riezzo G,Orlando A,Lonigro SL,Lavermicocca P

更新日期：2010-09-01 00:00:00

abstract：:This review discusses gastrointestinal manifestations of parathyroid diseases. Parathyroid hormone is the primary regulator of calcium physiology. Hypoparathyroidism can be idiopathic, hereditary, or secondary to surgery in the neck. Hyperparathyroidism is usually from adenomas or hyperplasia. Hypoparathyroidism is as...

journal_title：Journal of clinical gastroenterology

authors： Ebert EC

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:JC virus (JCV) is thought to infect approximately 80% of the human population. Antibodies against JCV can be found in the sera of many people with and without colorectal carcinoma (CRC). We hypothesized that JCV antibody titer will be higher in CRC patients than in healthy controls. AIM:To evaluate this hypo...

journal_title：Journal of clinical gastroenterology

authors： Niv Y,Vilkin A,Levi Z

更新日期：2010-08-01 00:00:00

abstract：:Cross-sectional imaging is frequently used in the diagnosis of pancreatic cysts, but there can be overlap in radiographic appearance. We present a case of a patient with presumed intraductal papillary mucinous neoplasm (IPMN) who was ultimately found to have a serous cystadenoma in communication with the pancreatic du...

journal_title：Journal of clinical gastroenterology

authors： Berman L,Mitchell KA,Israel G,Salem RR

更新日期：2010-07-01 00:00:00

abstract：:The main issue regarding the approach to the patient with uninvestigated dyspepsia is whether the symptoms are the result of an important clinical illness, which then determines the appropriate management strategy for the treatment of the symptoms. An initial trial of empiric antisecretory drugs is recommended for tho...

journal_title：Journal of clinical gastroenterology

authors： Graham DY,Rugge M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Deep biliary cannulation (DBC) is a prerequisite to most endoscopic retrograde cholangiopancreatographies (ERCPs). Numerous techniques have been described to maximize success and minimize ERCP-related complications, most notably post-ERCP pancreatitis. Dye-free cannulation by using guidewires with hydrophili...

journal_title：Journal of clinical gastroenterology

authors： Adler DG,Verma D,Hilden K,Chadha R,Thomas K

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To assess the therapeutic efficacy of 5-aminosalicylic acid (5-ASA) in patients with colonic diverticular disease performing a systematic review of the literature. DATA SOURCES:Cochrane Trial Register (until Issue 4, 2008), Medical Literature Analysis and Retrieval System Online (1966 to October 1, 2008), Ex...

journal_title：Journal of clinical gastroenterology

authors： Gatta L,Vakil N,Vaira D,Pilotto A,Curlo M,Comparato G,Leandro G,Ferro U,Lera M,Milletti S,Di Mario F

更新日期：2010-02-01 00:00:00

abstract：AIM:To investigate the effects of prolonged tricyclic antidepressants (TCAs) therapy on the frequency and duration of episodes of cyclic vomiting syndrome (CVS) in adults, and the global assessment of clinical improvement and the number of emergency department (ED) visits and/or hospitalizations. METHOD:An open labele...

journal_title：Journal of clinical gastroenterology

authors： Hejazi RA,Reddymasu SC,Namin F,Lavenbarg T,Foran P,McCallum RW

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Ascites due to cirrhosis may be difficult to distinguish from ascites due to heart failure by clinical features alone. More invasive testing is usually necessary, such as measurement of the hepatic venous pressure gradient, or paracentesis with measurement of the ascitic fluid total protein. AIM:The aim of ...

journal_title：Journal of clinical gastroenterology

authors： Sheer TA,Joo E,Runyon BA

更新日期：2010-01-01 00:00:00

abstract：GOALS:To define both risks and costs of optimal care of patients with gastric acid hypersecretion. BACKGROUND:The management of Zollinger-Ellison syndrome and other gastric acid hypersecretory disorders remains challenging. The optimal strategy for follow-up including gastric acid analysis, laboratory studies, and end...

journal_title：Journal of clinical gastroenterology

authors： Hirschowitz BI,Fineberg N,Wilcox CM,Mohnen J,Worthington J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Studies of serotonin reuptake transporter (SERT-P) polymorphism and irritable bowel syndrome (IBS) have shown diverse results among different populations, which might be due to racial and ethnic difference. AIM:This study was to investigate the potential association between the SERT-P polymorphism and clini...

journal_title：Journal of clinical gastroenterology

authors： Sikander A,Rana SV,Sinha SK,Prasad KK,Arora SK,Sharma SK,Singh K

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer (PC) is one of the leading causes of cancer death in Western countries. An increased risk for PC is known in a number of hereditary tumor syndromes. In selected individuals at high risk of developing PC, surveillance of the pancreas might be able to detect premalignant lesions and early inv...

journal_title：Journal of clinical gastroenterology

authors： Kluijt I,Cats A,Fockens P,Nio Y,Gouma DJ,Bruno MJ

更新日期：2009-10-01 00:00:00

abstract：:Patients affected by uncomplicated diverticular disease (DD) suffer from colicky, unexplained, recurrent, and short-lived but often debilitating abdominal pain and alteration in bowel habit. Although the goals of therapy, such as to improve symptoms and to prevent both recurrent attacks and complications, are clearly ...

journal_title：Journal of clinical gastroenterology

authors： Rocco A,Compare D,Caruso F,Nardone G

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Probiotic supplementation seems to provide beneficial effects in the prevention and treatment of radiation-induced diarrhea. We performed a systematic review and meta-analysis to estimate the efficacy of probiotic supplementation for prevention and treatment of radiation-induced diarrhea. METHODS:T...

journal_title：Journal of clinical gastroenterology

authors： Fuccio L,Guido A,Eusebi LH,Laterza L,Grilli D,Cennamo V,Ceroni L,Barbieri E,Bazzoli F

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Although of unproven benefit for nonalcoholic steatohepatitis (NASH), thiazolidinediones (TZDs) have emerged as a promising therapy. Little evidence exists, however, regarding sustained effects of TZDs in NASH after drug discontinuation. A recent clinical study suggests that relapse of NASH pathophysiology i...

journal_title：Journal of clinical gastroenterology

authors： Argo CK,Iezzoni JC,Al-Osaimi AM,Caldwell SH

更新日期：2009-07-01 00:00:00

abstract：:Patients who are hepatitis B surface antigen (HBsAg) positive are at risk for hepatitis flare when receiving cytotoxic or immunosuppressive therapy. It has been reported that as high as 50% of HBsAg-positive individuals who undergo chemotherapy develop elevation of liver transaminases. According to current Association...

journal_title：Journal of clinical gastroenterology

authors： Wu JM,Huang YH,Lee PC,Lin HC,Lee SD

更新日期：2009-05-01 00:00:00